C-21 modified epothilones

Details C-21 modified epothilones C-21 modified epothilones

C - Chemistry, Metallurgy

07

D

C07D 417/06 (2006.01) A01N 43/78 (2006.01) A01N 43/90 (2006.01) A61K 31/425 (2006.01) C07D 493/04 (2006.01)

Patent

CA 2360452

The invention is concerned with epothilones in which the thiazole substituent has been modified, with methods for their preparation and with antifungal or therapeutic agents which contain these epothilones.

L'invention concerne des épothilones dans lesquelles on a modifié le substituant thiazole, de même que des procédés de préparation de celles-ci. Elle concerne également des agents antifongiques ou thérapeutiques contenant ces épothilones.

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