C-6 ring-substituted pyrido¬1,2-a|benzimidazole derivatives...

C - Chemistry – Metallurgy – 07 – D

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C07D 471/04 (2006.01) A61K 31/437 (2006.01) A61P 25/00 (2006.01) C07D 221/00 (2006.01) C07D 235/00 (2006.01)

Patent

CA 2391766

A C-6 ring-substituted pyrido[1,2-<i>a</i>]benzimidazole derivative of formula (1): methods of preparation and pharmaceutical compositions containing a substituted pyrido[1,2-<i>a</i>]benzimidazole derivative as the active ingredient are disclosed. The substituted pyrido[1,2-<i>a</i>]benzimidazole derivatives are useful in the treatment of central nervous system disorders.

L'invention concerne un dérivé de pyrido[1,2-a]benzimidazole substitué en C-6 représenté par la formule (1). L'invention concerne également des procédés de préparation ainsi que des compositions pharmaceutiques contenant un dérivé de pyrido[1,2-a]benzimidzole substitué ayant la fonction d'un ingrédient actif. Ces dérivés de pyrido[1,2-a]benzimidazole substitués sont utiles dans le traitement des troubles du système nerveux central.

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