C-fms kinase inhibitors

Details C-fms kinase inhibitors C-fms kinase inhibitors

C - Chemistry, Metallurgy

07

D

C07D 233/90 (2006.01) A61K 31/501 (2006.01) A61P 35/00 (2006.01) C07D 401/12 (2006.01) C07D 403/12 (2006.01) C07D 405/12 (2006.01)

Patent

CA 2649512

The invention is directed to compounds of Formula II: wherein A, R1, R2, R3, R4, X, Y and W are set forth in the specification, as well as solvates, hydrates, tautomers or pharmaceutically acceptable salts thereof, that inhibit protein tyrosine kinases, especially c-fms kinase.

L'invention concerne des composés de Formule II dans laquelle A, R1, R2, R3, R4, X, Y et W sont définis dans la description ainsi que des solvates, des hydrates, des tautomères ou des sels pharmaceutiquement acceptables de ceux-ci qui inhibent les protéine tyrosine kinases, notamment la c-fms kinase.

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