C-fms kinase inhibitors

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 307/72 (2006.01) A61K 31/55 (2006.01) A61P 35/00 (2006.01) C07D 207/34 (2006.01) C07D 207/42 (2006.01) C07D 213/81 (2006.01) C07D 231/16 (2006.01) C07D 261/18 (2006.01) C07D 295/14 (2006.01) C07D 307/68 (2006.01) C07D 401/12 (2006.01) C07D 405/12 (2006.01) C07D 491/04 (2006.01)

Patent

CA 2536964

The invention is directed to compounds of formulae (I), (II) and (III), wherein A, R1, R2, R3, R4, X, Y and W are set forth in the specification, as well as solvates, hydrates, tautomers or pharmaceutically acceptable salts thereof, that inhibit protein tyrosine kinases, especially c-fms kinase.

L'invention concerne des composés de formules (I), (II) et (III), dans lesquelles A, R¿1?, R¿2?, R¿3?, R¿4?, X, Y et W sont tels que définis dans la description, ainsi que des solvates, des hydrates, des tautomères ou des sels pharmaceutiquement acceptables de ceux-ci, qui inhibent les protéines tyrosines kinases, en particulier la kinase c-fms.

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