C-met modulators and method of use

Details C-met modulators and method of use C-met modulators and method of use

C - Chemistry, Metallurgy

12

Q

C12Q 1/48 (2006.01) C07D 215/233 (2006.01) C12N 9/12 (2006.01)

Patent

CA 2744997

The present invention provides compounds for modulating protein kinase enzymatic activity for modulating cellular activities such as proliferation, differentiation, programmed cell death, migration and chemoinvasion. More specifically, the invention provides quinazolines and quinolines which inhibit, regulate and/or modulate kinase receptor, particularly c-Met, KDR, c-Kit, flt-3 and flt-4, signal transduction pathways related to the changes in cellular activities as mentioned above, compositions which contain these compounds, and methods of using them to treat kinase-dependent diseases and conditions. The present invention also provides methods for making compounds as mentioned above, and compositions which contain these compounds.

Affiliated with

Also associated with

Rating

C-met modulators and method of use does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with C-met modulators and method of use, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and C-met modulators and method of use will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1433903