C-met modulators and methods of use

Details C-met modulators and methods of use C-met modulators and methods of use

C - Chemistry, Metallurgy

07

D

C07D 401/12 (2006.01) A61K 31/47 (2006.01) A61K 31/517 (2006.01) C07D 401/14 (2006.01)

Patent

CA 2603748

The present invention provides compounds, which have activity for modulating protein kinase enzymatic activity and are potentially useful for modulating cellular activities such as, e.g., proliferation, differentiation, programmed cell death, migration and chemoinvasion. The present invention also provides compositions containing such compounds, and methods for producing and using such compounds and compositions.

La présente invention propose des composés, qui ont une activité pour moduler l~activité enzymatique de la protéine kinase et qui sont potentiellement utiles pour moduler des activités cellulaires telles que, par exemple, la prolifération, la différenciation, la mort programmée de la cellule, la migration et la chimio-invasion. La présente invention propose aussi des compositions contenant de tels composés, et des procédés pour produire et utiliser de tels composés et compositions.

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