C-nitroso-derived nitroxyl donors

Details C-nitroso-derived nitroxyl donors C-nitroso-derived nitroxyl donors

C - Chemistry, Metallurgy

07

C

C07C 211/00 (2006.01) A61K 31/24 (2006.01)

Patent

CA 2648384

Active compounds of Formula (I) are described: wherein: R1 and R2 are each independently C1-C4 alkyl; or R1 and R2 together form a C2-C7 alkylene chain; and Z is a non-steroidal anti-inflammatory drug (NSAID); along with pharmaceutically acceptable salts and prodrug thereof, and methods of using the same.

La présente invention concerne des composés actifs de formule (I) où : R1 et R2 sont chacun un C1-C4 alkyle ; ou R1 et R2 forment ensemble une chaîne C2-C7 alkylène ; et Z est un anti-inflammatoire non stéroïdien (AINS) ; ainsi que des sels pharmaceutiquement acceptables et leurs promédicaments, et leurs procédés d'utilisation.

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