C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 471/04 (2006.01) A61K 31/4375 (2006.01) A61P 35/00 (2006.01) C07D 471/14 (2006.01) C07D 491/147 (2006.01) C07D 495/14 (2006.01)
Patent
CA 2745071
Disclosed are C-ring modified tricyclic benzonaphthiridinone compounds and analogs thereof, pharmaceutical compositions comprising such compounds and processes for preparing the same. The compounds are useful in the treatment of diseases amenable to protein kinase signal transduction inhibition, regulation and/or modulation.
L'invention porte sur des composés benzonaphtyridinones tricycliques modifiés sur le noyau C et des analogues de ceux-ci, des compositions pharmaceutiques comprenant de tels composés et des procédés pour leur préparation. Les composés sont utiles dans le traitement de maladies sensibles à l'inhibition, la régulation et/ou la modulation de la transduction du signal de protéines kinases.
Huck Bayard R.
Karra Srinivasa R.
Richardson Thomas E.
Sutton Amanda E.
Xiao Yufang
Kirby Eades Gale Baker
Merck Patent Gmbh
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