C1 inhibitor muteins and uses thereof

Details C1 inhibitor muteins and uses thereof C1 inhibitor muteins and uses thereof

C - Chemistry, Metallurgy

12

N

C12N 15/15 (2006.01) A61K 38/55 (2006.01) C07K 14/81 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2071871

2071871 9106650 PCTABS00005 Compositions consisting of C1 inhibitor muteins having biological activity similar to C1 inhibitor, but with enhanced resistance to proteolytic cleavage thus rendering such muteins suitable as anti-inflammatory agents, preferably for the treatment or prevention of sepsis.

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