C1 inhibitor produced in the milk of transgenic mammals

Details C1 inhibitor produced in the milk of transgenic mammals C1 inhibitor produced in the milk of transgenic mammals

C - Chemistry, Metallurgy

12

N

C12N 15/00 (2006.01) A01K 67/027 (2006.01) A23C 9/00 (2006.01) A61K 31/02 (2006.01) A61K 38/57 (2006.01) C07K 14/81 (2006.01) C12N 15/85 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2398707

The invention provides transgenic nonhuman mammals expressing C1 inhibitor in their milk. The C1 inhibitor is useful in treating patients with hereditary angioedema or patients requiring immunosuppression.

L'invention concerne des mammifères non humains transgéniques exprimant un inhibiteur de C1 dans leur lait. L'inhibiteur de C1 est utile pour traiter des patients atteint d'oedème angioneurotique héréditaire ou des patients nécessitant une immunosuppression.

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