C10 cyclopropyl ester substituted taxane compositions

Details C10 cyclopropyl ester substituted taxane compositions C10 cyclopropyl ester substituted taxane compositions

A - Human Necessities

61

K

A61K 31/337 (2006.01) A61K 31/34 (2006.01)

Patent

CA 2597682

Compositions comprising a taxane having a cyclopropyl ester substituent at C10, a keto substituent at C9, a hydroxy substituent at C7, a 2-furyl substituent at C3.prime. and an isobutoxycarbamate substituent at C3.prime..

L'invention concerne des compositions comprenant un taxane comportant une substitution cyclopropyl ester en C10, un substituant céto en C9, un substituant hydroxy en C7, un substituant 2-furyle en C3' et un substituant isobutoxycarbamate en C3'.

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