C10 ester substituted taxanes as antitumor agents

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 305/14 (2006.01) A61K 31/335 (2006.01) A61K 31/337 (2006.01) A61K 31/341 (2006.01) A61K 31/381 (2006.01) A61K 31/4427 (2006.01) A61P 35/00 (2006.01) A61P 35/04 (2006.01) C07D 311/00 (2006.01) C07D 405/12 (2006.01) C07D 405/14 (2006.01) C07D 407/12 (2006.01) C07D 407/14 (2006.01) C07D 409/12 (2006.01) C07D 409/14 (2006.01)

Patent

CA 2368274

Taxanes having an ester substituent at C(10), a hydroxy substituent at C(7), and a range of C(2), C(9), C(14), and side chain substituents.

L'invention concerne des taxanes comportant un susbtituant ester en C(10), un substituant hydroxy en C(7), et une gamme de substituants de C(2), C(9), C(14) et de chaîne latérale.

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