C4 binding protein fusion proteins

Details C4 binding protein fusion proteins C4 binding protein fusion proteins

C - Chemistry, Metallurgy

12

N

C12N 15/62 (2006.01) A61K 38/17 (2006.01) A61K 47/48 (2006.01) A61K 49/00 (2006.01) C07K 14/47 (2006.01) C07K 14/73 (2006.01) C07K 19/00 (2006.01) C12N 7/01 (2006.01) C12N 15/12 (2006.01) G01N 33/566 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2049964

2049964 9111461 PCTABS00006 This invention relates to multimeric and hetero-multimeric C4 binding protein (C4bp) fusion proteins and compositions and methods using them. More particularly, this invention relates to multimeric C4bp fusion proteins which are aggregates or assemblies of C4bp monomers linked to functional moieties. It also relates to C4bp fusion polypeptides and in particular CD4-C4bp fusion polypeptides comprising an amino acid sequence for a soluble human CD4 protein fused to a C4bp monomer having, preferably, four short consensus repeat regions.

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