C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 211/60 (2006.01) A61K 31/445 (2006.01) A61K 31/4523 (2006.01) C07D 401/04 (2006.01) C07D 401/06 (2006.01) C07D 401/10 (2006.01) C07D 401/12 (2006.01) C07D 405/12 (2006.01) C07D 413/12 (2006.01)
Patent
CA 2747522
Compounds are provided that are modulators of the C5a receptor. The compounds are substituted piperidines and are useful in pharmaceutical compositions, methods for the treatment of diseases and disorders involving the pathologic activation of C5a receptors.
L'invention porte sur des composés qui sont des modulateurs du récepteur de C5a. Les composés sont des pipéridines substituées, et sont utiles dans des compositions pharmaceutiques. L'invention porte également sur des méthodes de traitement de maladies et de troubles mettant en jeu l'activation pathologique de récepteurs de C5a.
Fan Pingchen
Greenman Kevin Lloyd
Leleti Manmohan Reddy
Li Yandong
Powers Jay
Chemocentryx Inc.
Fetherstonhaugh & Co.
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