C7 taxane derivatives and pharmaceutical compositions...

Details C7 taxane derivatives and pharmaceutical compositions... C7 taxane derivatives and pharmaceutical compositions...

C - Chemistry, Metallurgy

07

D

C07D 305/14 (2006.01) A61K 31/38 (2006.01) A61K 31/395 (2006.01) A61K 31/44 (2006.01) A61K 31/695 (2006.01) C07D 405/00 (2006.01) C07D 407/00 (2006.01) C07D 407/12 (2006.01) C07D 409/00 (2006.01) C07D 409/12 (2006.01) C07F 7/10 (2006.01)

Patent

CA 2155018

Taxane derivatives having alternative C7 substituents wherein the substituents are independently selected from the group consisting of hydrogen and acyloxy. The derivatives are valuable antileukemia and antitumor agents. The taxane has the formula (see formula 3).

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