Caax prenyl protease nucleic acids and polypeptides and...

C - Chemistry – Metallurgy – 12 – N

Patent

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C12N 15/82 (2006.01) C12N 9/50 (2006.01) C12N 15/57 (2006.01)

Patent

CA 2456050

The present invention provides novel isolated prenyl protease polynucleotides and polypeptides encoded by the prenyl protease polynucleotides. Also provided are the antibodies that immunospecifically bind to a prenyl protease polypeptide or any derivative, variant, mutant or fragment of the prenyl protease polypeptide, polynucleotide or antibody. The invention additionally provides methods of constructing transgenic plants that have altered levels of prenyl protease polynucleotides and polypeptides. Methods for identifying prenyl protease enzymes substrates and inhibitors are also provided.

La présente invention concerne des nouveaux polynucléotides de la prényl protéase isolés et des polypeptides codés par les polynucléotides de la prényl protéase. Cette invention a également trait aux anticorps qui se lient de manière immunospécifique à un polypeptide de la prényl protéase ou à tout dérivé, variant, mutant ou fragment du polypeptide, du polynucléotide ou de l'anticorps de la prényl protéase. Ladite invention a également pour objet des méthodes d'élaboration de plantes transgéniques qui présentent des niveaux altérés de polynucléotides et de polypeptides de la prényl protéase, ainsi que des méthodes d'identification d'inhibiteurs et de substrats d'enzymes de la prényl protéase.

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