Cadherin-11 antagonists and methods for the treatment of...

Details Cadherin-11 antagonists and methods for the treatment of... Cadherin-11 antagonists and methods for the treatment of...

C - Chemistry, Metallurgy

07

K

C07K 16/28 (2006.01) A61K 38/17 (2006.01)

Patent

CA 2711394

The present invention relates to Cadherin-11 antagonists and compositions comprising Cadherin-11 antagonists. The invention also relates to methods for treating inflammatory joint disorders, such as rheumaotid arthritis, in a mammalian subject by administering a therapeutically effective amount of a Cadherin-11 antagonist.

La présente invention porte sur des antagonistes de cadhérine-11 et sur des compositions comprenant des antagonistes de cadhérine-11. L'invention porte également sur des procédés de traitement de troubles inflammatoires des articulations, tels que la polyarthrite rhumatoïde, chez un sujet mammifère par administration d'une quantité thérapeutiquement efficace d'un antagoniste de cadhérine-11.

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