Cadherin materials and methods

C - Chemistry – Metallurgy – 12 – N

Patent

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C12N 15/12 (2006.01) A61K 39/395 (2006.01) C07K 14/705 (2006.01) C07K 16/28 (2006.01) C12N 5/18 (2006.01) C12P 21/08 (2006.01)

Patent

CA 2111573

DNA sequences encoding novel cadherins, designated cadherins-4 through -12, are disclosed along with methods and ma- terials for the recombinant production of the same. Antibody substances specific for the novel cadherins and cadherin peptides are disclosed as useful for modulating the natural binding and/or regulatory activities of the cadherins.

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