Calcified tissue facing preparation containing an...

A - Human Necessities – 61 – K

Patent

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A61K 6/08 (2006.01) A61C 5/04 (2006.01) A61K 6/083 (2006.01)

Patent

CA 2344697

The present invention provides a calcified tissue facing preparation characterized by having a polymerizable resin, and an antimicrobial agent of formula (I) where R1 is a hydrocarbon radical having between 1 and 16 carbon atoms, n is an integer between 1 and 8 inclusive and X is a halogen atom selected from fluorine, chlorine or bromine. It is appreciated that R1 includes unsaturated hydrocarbon radicals, as well as heteroatom containing radicals. Preferably, the molecule of formula (I) is associated with an adduct species. A solvent and the complementary spectrum antimicrobial benzalkonium chloride are also optionally added. An antimicrobial oral rinse excluding the polymerizable resin contains at least 0.2 % by weight of the antimicrobial agent.

La présente invention concerne une préparation d'incrustation vestibulaire pour tissus calcifiés, cette préparation renfermant une résine polymérisable et un agent bactéricide de formule (I), dans laquelle R¿1? représente un radical hydrocarboné présentant 1 à 16 atomes de carbone, n désigne un nombre entier variant entre 1 et 8, et X symbolise un atome d'halogène choisi parmi le fluor, le chlore, ou le brome, R¿1? comprenant des radicaux hydrocarbonés insaturés ainsi que des radicaux contenant des hétéroatomes. La molécule de formule (I) est de préférence associée à une espèce d'un produit d'addition, un solvant et du chlorure de benzalkonium bactéricide à spectre d'activité complémentaire étant éventuellement ajoutés. Un collutoire bactéricide exempt de résine polymérisable contient au moins 0,2 % en poids dudit agent bactéricide.

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