Calcineurin-like human phosphoesterase

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/55 (2006.01) A01K 67/027 (2006.01) A61K 38/46 (2006.01) C07K 16/40 (2006.01) C12N 5/10 (2006.01) C12N 9/16 (2006.01) C12N 15/11 (2006.01) C12Q 1/44 (2006.01) G01N 33/573 (2006.01)

Patent

CA 2503491

This invention provides compositions, organisms and methodologies employing a novel human gene encoding a protein that has sequence homology to a consensus sequence of calcineurin-like phosphoesterase family are disclosed. The novel protein is encoded by a human gene comprising 4 exons. The human gene is localized in the 10p15 locus of human chromosome 10. The sequence similarities between the novel human protein and the consensus sequence of calcineurin-like phosphoesterases indicate that the novel human protein may function as a calcineurin-like protein phosphatase.

La présente invention se rapporte à des compositions, à des organismes et à des procédés faisant appel à un nouveau gène humain codant une protéine qui présente une homologie de séquence avec une séquence consensus de la famille des phosphoestérases de type calcineurine. La nouvelle protéine est codée par un gène humain comprenant 4 exons. Le gène humain est localisé dans le locus 10p15 du chromosome humain 10. Les similarités de séquence entre la nouvelle protéine humaine et la séquence de consensus des phosphoestérases de type calcineurine indiquent que la nouvelle protéine humaine peut jouer le rôle d'une protéine phosphatase de type calcineurine.

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