A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/513 (2006.01) A61K 31/4418 (2006.01) A61K 31/4422 (2006.01) A61K 31/4439 (2006.01) A61K 31/505 (2006.01) A61K 31/506 (2006.01) A61P 9/12 (2006.01) G01N 33/15 (2006.01) G01N 33/50 (2006.01)
Patent
CA 2498282
The present invention is directed in part towards methods of modulating the function of calcium channels with dihydropyrimidine, dihydropyrimidone, dihydropyrimidinethione, and dihydropyridine compounds. In addition, the invention describes methods of preventing and treating protein kinase-related abnormal conditions in organisms with a compound identified by the invention. Furthermore, the invention pertains to T-channel agonists that have a slow onset of activity and long duration of activity.
La présente invention concerne en partie des méthodes qui permettent de moduler la fonction des canaux calciques lents avec des composés de dihydropyrimidine, dihydropyrimidone, dihydropyrimidinethione et dihydropyridine. Elle concerne également des méthodes de prévention et de traitement d'états anormaux associés à la protéine kinase dans des organismes, à l'aide d'un composé de l'invention. L'invention concerne en outre des agonistes des canaux T, dont l'action est lente au début mais de longue durée.
Bibbs Jeffrey A.
Rao Srirama
Diakron Pharmaceuticals Inc.
Robic
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