Calcium channel blocking polypeptides from filistata hibernalis

Details Calcium channel blocking polypeptides from filistata hibernalis Calcium channel blocking polypeptides from filistata hibernalis

C - Chemistry, Metallurgy

07

K

C07K 14/435 (2006.01) A01N 37/18 (2006.01) A01N 43/38 (2006.01) A01N 63/00 (2006.01) A61K 38/17 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2134889

Polypeptides isolated from the venom of the Filistata hibernalis spider block calcium channels in cells of various organisms and are useful in blocking said calcium channels in cells, per se, in the treatment of calcium channel-mediated diseases and conditions and in the control of invertebrate pests.

Des polypeptides isolés du venin de l'araignée de l'espèce Filistata hibernalis bloquent les canaux à calcium dans les cellules de différents organismes et sont utiles pour bloquer les canaux en question dans les cellules, en soi, dans le traitement des maladies dans lesquelles interviennent les canaux à calcium et dans la répression des invertébrés nuisibles.

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