A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 47/02 (2006.01) A61K 9/00 (2006.01) A61K 31/198 (2006.01) A61K 33/00 (2006.01) A61K 38/44 (2006.01) A61K 47/30 (2006.01) A61K 47/34 (2006.01) A61L 27/02 (2006.01) A61L 27/42 (2006.01) A61L 27/54 (2006.01) C12N 5/00 (2006.01) C12N 11/14 (2006.01)
Patent
CA 2669457
The present invention generally relates to calcium-containing structures and methods of using the structures. In one aspect, the porous or hollow microstructures or particulates contain nitric oxide or a nitric oxide forming compound. The hollow calcium containing microstructures are used in conjunction with bone tissues/by-products to augment bone defects and extend the supply of bone tissues/by-products for bone augmentation. Bonding agents, such as calcium cements, are also used in the preparation of the hollow calcium microstructures combined with bone tissues/by-products or for use in preparing the hollow microstructures. The calcium-containing microstructures of the present invention are also useful as delivery vehicles of nitric oxide and/or nitric oxide containing or producing compounds for a variety of in vitro and in vivo uses. Calcium containing contoured substrates upon which cells/tissues can be grown in vitro for replacement and repair of tissues in vivo that conform in size and shape to the tissue surface to be replaced are also provided.
Starling Brian L.
Stephan James E.
Cap Biotechnology Inc.
Goodwin Mckay
LandOfFree
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