A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 48/00 (2006.01) A61K 9/00 (2006.01) A61K 9/16 (2006.01) A61K 47/48 (2006.01) A61L 24/02 (2006.01) A61L 27/12 (2006.01) A61L 27/32 (2006.01) A61L 27/34 (2006.01) C01B 25/16 (2006.01) C01B 25/32 (2006.01) C04B 28/34 (2006.01) C04B 40/00 (2006.01) C04B 41/50 (2006.01) C04B 41/87 (2006.01) C12N 15/87 (2006.01) A61F 2/00 (2006.01) A61F 2/28 (2006.01) A61F 2/30 (2006.01) A61F 2/46 (2006.01)
Patent
CA 2511820
The invention relates to a method of modifying the surface of calcium phosphate ceramics and powders. The inventive method involves maturation in a culture medium, thereby causing epitaxial carbonated apatite growth at the surface of the aforementioned ceramics and powders. The invention also relates to the use of said modified ceramics and powders for in vitro and in vivo cell transfection and for cell culture in a three-dimensional network.
La présente invention se rapporte à un procédé pour modifier la surface des poudres et des céramiques de phosphates de calcium comprenant une maturation dans un milieu de culture entraînant une croissance épitaxique d'apatite carbonatée à la surface desdites poudres et céramiques. L'invention porte également sur l'utilisation desdites poudres et céramiques modifiées pour la transfection de cellules in vitro et in vivo et pour la culture en réseau tridimensionnel.
Frayssinet Patrick Pierre
Rouquet Nicole Francine
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
Urodelia
LandOfFree
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