Calcium phosphate delivery vehicles for osteoinductive proteins

Details Calcium phosphate delivery vehicles for osteoinductive proteins Calcium phosphate delivery vehicles for osteoinductive proteins

A - Human Necessities

61

K

A61K 38/18 (2006.01) A61K 31/19 (2006.01) A61K 31/70 (2006.01) A61K 31/715 (2006.01) A61K 31/74 (2006.01) A61K 33/06 (2006.01) A61K 33/10 (2006.01) A61K 33/14 (2006.01) A61K 33/42 (2006.01) A61K 38/00 (2006.01) A61K 38/02 (2006.01) A61K 47/02 (2006.01) A61L 24/02 (2006.01) A61L 24/10 (2006.01) A61L 27/12 (2006.01) A61L 27/22 (2006.01) A61P 19/08 (2006.01)

Patent

CA 2449713

A composition for treating a mammal having a bone defect. The composition comprises an osteogenic protein, a calcium phosphate material as a carrier, and an effective amount of an effervescent agent. Methods of making the compositions and methods of using the osteogenic compositions to treat osteoporotic and/or osteopenic bone are also disclosed.

L'invention concerne une composition de traitement d'un mammifère souffrant d'un déficit osseux. Cette composition contient une protéine ostéogène, du phosphate de calcium comme excipient, et une dose efficace d'agent effervescent. Par ailleurs, l'invention concerne des procédés de fabrication de ces compositions ainsi que des méthodes d'utilisation des compositions ostéogènes pour traiter l'ostéoporose et/ou l'ostéopénie.

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