Calcium receptor-active arylalkyl amines

Details Calcium receptor-active arylalkyl amines Calcium receptor-active arylalkyl amines

C - Chemistry, Metallurgy

07

C

C07C 217/58 (2006.01) A61K 31/13 (2006.01) A61K 31/135 (2006.01) A61K 31/165 (2006.01) A61K 31/275 (2006.01) A61K 31/36 (2006.01) C07C 211/27 (2006.01) C07C 211/29 (2006.01) C07C 211/30 (2006.01) C07C 215/50 (2006.01) C07C 217/62 (2006.01) C07C 219/28 (2006.01) C07C 237/30 (2006.01) C07C 255/58 (2006.01) C07C 323/32 (2006.01) C07D 317/58 (2006.01)

Patent

CA 2173747

The present invention features molecules with general structure (I) or (II) which can modulate on or activities of an inorganic ion receptor. Preferably, the molecule can mimic or block the effect of extracellular Ca2+ on a calcium receptor. The preferred use of such molecules is to treat diseases or disorders by altering inorganic ion receptor activity, preferably calcium receptor activity.

La présente invention concerne des molécules ayant la structure générale (I) ou (II) et qui sont capables de moduler l'activité d'un récepteur d'ions inorganiques. La molécule peut de préférence simuler ou bloquer l'effet du Ca?2+¿ extracellulaire sur un récepteur du calcium. L'utilisation préférée de ces molécules concerne le traitement de maladies ou d'affections par modification de l'activité de récepteurs d'ions inorganiques, de préférence l'activité de récepteurs du calcium.

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