Calcium salts of lipopeptide antibiotics, method for...

C - Chemistry – Metallurgy – 07 – K

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C07K 7/56 (2006.01) A61K 38/12 (2006.01) A61P 31/04 (2006.01) C07K 7/54 (2006.01) C07K 7/60 (2006.01)

Patent

CA 2322052

The invention relates to a calcium salt of the compound of formula (II), where R1 is a straight-chain or branched, saturated or unsaturated aliphatic acyl rest with between 8 and 22 carbon atoms, which can optionally be interrupted by or linked to one or more phenyl or cycloalkyl groups and optionally interrupted by oxygen. The invention also relates to a method for producing said calcium salt and to its use as a medicine.

L'invention concerne un sel de calcium du composé de formule (II), dans laquelle R1 représente un radical acyle aliphatique à chaîne linéaire ou ramifié, saturé ou insaturé, comportant 8 à 22 atomes de carbone, pouvant éventuellement être interrompu par au moins un groupe phényle ou cycloalkyle, ou lié à ces groupes, et pouvant éventuellement être interrompu par de l'oxygène. L'invention concerne également un procédé de production dudit sel et son utilisation comme médicament.

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