Calixarene-based peptide conformation mimetics, methods of...

A - Human Necessities – 61 – K

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A61K 31/015 (2006.01) A61K 31/09 (2006.01) A61K 31/135 (2006.01) A61K 31/155 (2006.01) A61K 31/216 (2006.01) A61K 31/4192 (2006.01) A61P 9/10 (2006.01) A61P 15/00 (2006.01) A61P 19/02 (2006.01) A61P 27/02 (2006.01) A61P 27/06 (2006.01) A61P 31/04 (2006.01) A61P 35/00 (2006.01) A61P 43/00 (2006.01)

Patent

CA 2583092

A class of topomimetic calixarene-based peptide mimetics is described. Calixarene-based peptide mimetics have various biological activities such as, for example, bactericidal activity, antiangiogenic activity, and/or antitumor activity. Methods of use and methods of designing calixarene-based peptide mimetics are described.

L'invention concerne une classe de mimétiques peptidiques à base de calixarène de type topomimétique, ayant diverses activités biologiques comme, par exemple, l'activité bactéricide, l'activité antiangiogénique, et/ou l'activité antitumorale. On décrit aussi des procédés d'utilisation et des procédés de conception de ces mimétiques.

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