Camel, an alternative translation product of the tumour...

Details Camel, an alternative translation product of the tumour... Camel, an alternative translation product of the tumour...

C - Chemistry, Metallurgy

12

N

C12N 15/12 (2006.01) A61K 38/17 (2006.01) C07K 14/47 (2006.01) A61K 38/00 (2006.01) A61K 39/00 (2006.01)

Patent

CA 2346942

The tumor-associated antigen CAMEL and DNA encoding it. The tumor-associated antigen is encoded by an open reading frame of the LAGE-1 gene. The tumor- associated antigen, immunogenic (poly)peptides derived therefrom and DNAs encoding them, are useful for cancer immunotherapy.

Cette invention a trait à un antigène, CAMEL, associé à une tumeur, et à l'ADN le codant. Cet antigène est codé par un cadre de lecture ouvert du gène LAGE-1. Cet antigène associé à une tumeur, les (poly)peptides immunogènes dérivés de cet antigène et les ADN les codant se révèlent des plus utiles en matière de thérapie anticancéreuse.

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