C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/13 (2006.01) A61K 39/395 (2006.01) A61P 11/06 (2006.01) A61P 31/06 (2006.01) A61P 31/16 (2006.01) A61P 35/00 (2006.01) C07K 16/10 (2006.01) C07K 16/12 (2006.01) C07K 16/18 (2006.01) C07K 16/24 (2006.01) C07K 16/28 (2006.01) C07K 16/30 (2006.01) C07K 16/36 (2006.01) C07K 16/40 (2006.01) C07K 16/42 (2006.01)
Patent
CA 2505326
The invention relates to a method suitable for administering protein therapeutic molecules orally, sublingually, topically, intravenously, subcutaneously, nasally, vaginally, rectally or by inhalation so as to avoid inactivation, by using VHH polypeptides derived from Camelidae antibodies. The invention further relates to the said therapeutic molecules. The invention further a method for delivering therapeutic molecules to the interior of cells. The invention furthe relates to anti-IgE therapeutic molecules.
L'invention concerne un procédé adapté à l'administration orale, sublinguale, topique, intraveineuse, sous-cutanée, nasale, vaginale, rectale ou par inhalation de molécules thérapeutiques de protéine afin d'éviter l'inactivation, à l'aide de polypeptides VHH dérivés d'anticorps de camélidés. L'invention concerne aussi ces molécules thérapeutiques. Elle concerne encore un procédé d'administration de ces molécules à l'intérieur des cellules. Elle concerne encore des molécules thérapeutiques anti-IgE.
Silence Karen
Vaeck Mark
Van Bergen En Henegouwen Paul P. M. P.
Ablynx N.v.
Borden Ladner Gervais Llp
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