C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
195/1.2, 195/1.2
C12N 15/00 (2006.01) C07K 14/47 (2006.01) C12N 1/00 (2006.01) C12N 15/67 (2006.01) C12N 15/85 (2006.01) C12P 21/00 (2006.01)
Patent
CA 2003345
ABSTRACT OF THE INVENTION This invention is directed toward the characterization and cloning of a cAMP-responsive transcription enhancer binding protein (CREB). This protein, CREB, is a transcriptional activator which activates transcription in eukaryotic cells. This CREB protein can be used to increase or decrease production of proteins by stimulating expression of a recombinant gene that is operably-linked to the CRE enhancer element and responsive to cAMP. A86-05.WP 111888
Habener Joel F.
Hoeffler James P.
Gowling Lafleur Henderson Llp
The General Hospital Corporation
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