Cancer associated protein kinases and their uses

C - Chemistry – Metallurgy – 12 – N

Patent

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C12N 15/54 (2006.01) A61K 31/7088 (2006.01) A61K 48/00 (2006.01) A61P 35/00 (2006.01) C12N 9/12 (2006.01) C12N 9/99 (2006.01) C12Q 1/48 (2006.01) C12Q 1/68 (2006.01) C40B 30/04 (2006.01) G01N 33/573 (2006.01) G01N 33/574 (2006.01)

Patent

CA 2423039

Detection of expression of the provided protein kinase in cancers is useful as a diagnostic, for determining the effectiveness of drugs, and determining patient prognosis. The encoded polypeptides further provides a target for screening pharmaceutical agents effective in inhibiting the growth or metastasis of tumor cells.

On utilise la détection de l'expression de la protéine kinase décrite dans des cancers comme diagnostic pour déterminer l'efficacité de médicaments et établir un pronostic du patient. Les polypeptides codés constituent une cible utile au criblage d'agents pharmaceutiques permettant d'inhiber la croissance ou la métastase de cellules tumorales.

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