C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 7/06 (2006.01) C07K 7/08 (2006.01) C07K 14/47 (2006.01) G01N 33/574 (2006.01) G01N 33/68 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2408297
A novel RMP homologue is provided, as well as nucleic acids encoding the protein and antisense nucleic acids. Methods of diagnosing conditions dependent on RMP are provided as well as screening methods for identifying agents active against conditions dependent on RMP, such as conditions dependent on amino acid regulation, cancer, neurodegeneration, muscle degeneration, immune disorders, and AIDS.
L'invention concerne un homologue RMP (protéine à médiation RPB5), des acides nucléiques codant pour cette protéine et des acides nucléiques antisens. Elle concerne aussi des méthodes de diagnostic de troubles associés à RMP ainsi que des méthodes de criblage destinées à identifier des agents actifs contre des troubles associés à RMP, tels que des troubles associés à une régulation d'acide aminé, un cancer, une neurodégénérescence, une dégénérescence musculaire, des troubles immunitaires, et au sida.
Gstaiger Matthias Georg Christian
Krek Wilhelm
Fetherstonhaugh & Co.
Novartis Forschungsstiftung Zweigniederlassung Friedrich Miesche
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