G - Physics – 01 – N
Patent
G - Physics
01
N
G01N 33/574 (2006.01) C12N 15/02 (2006.01) C12N 15/09 (2006.01)
Patent
CA 2565175
A method of cancer diagnosis characterized in that ROBO1 protein is detected. Further, there is disclosed a method of treating diseases attributed to abnormal cell growth, comprising administering an antibody capable of binding to ROBO1, and are disclosed, comprising an antibody capable of binding to ROBO1 as an active ingredient, a pharmaceutical composition, cytostatic agent and anticancer agent. Still further, there is disclosed a method of inhibiting the growth of ROBO1 expression cells or method of inducing cytotoxicity in ROBO1 expression cells, comprising bringing an antibody capable of binding to ROBO1 into contact with ROBO1 expression cells. Moreover, there is disclosed a method of monitoring the intensification of hepatitis severity, comprising detection of ROBO1 protein.
Un procédé de diagnostic du cancer caractérisé du fait qu~une protéine ROBO1 est décelée. De plus, il est décrit un procédé pour traiter des maladies attribuées à une croissance cellulaire anormale, comprenant l~administration d~un anticorps susceptible de se lier au ROBO1, et sont décrits, y compris un anticorps susceptible de se lier au ROBO1 en tant que principe actif, une composition pharmaceutique, un agent cytostatique et un agent anti-cancéreux. En outre encore, il est décrit un procédé d~inhibition de la croissance de cellules d~expression ROBO1 ou un procédé d~induction de la cytotoxicité dans des cellules d~expression ROBO1, comprenant la mise en contact d~un anticorps susceptible de se lier au ROBO1 avec des cellules d~expression ROBO1. De plus, il est décrit un procédé de surveillance de l~intensification de la gravité de l~hépatite comprenant la détection de la protéine ROBO1.
Aburatani Hiroyuki
Arai Masahiro
Fukayama Masashi
Funahashi Shin-Ichi
Hippo Yoshitaka
Aburatani Hiroyuki
Chugai Seiyaku Kabushiki Kaisha
Smart & Biggar
LandOfFree
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