G - Physics – 01 – N
Patent
G - Physics
01
N
G01N 33/48 (2006.01) C12Q 1/02 (2006.01) C12Q 1/68 (2006.01) C12Q 3/00 (2006.01) G01N 15/14 (2006.01) G01N 21/64 (2006.01) G01N 33/53 (2006.01) G01N 35/00 (2006.01) C12N 5/06 (2006.01)
Patent
CA 2494928
The invention is based on the discovery that occurrence of centrosomal abnormalities in cells correlates with the occurrence of cancer, and that the greater the degree of the centrosomal abnormalities, the greater the probability of cancer occurring and the severity of the cancer. The invention includes methods of detecting centrosome abnormalities in tissue samples. It provides new methods for predicting and diagnosing cancer.
L'invention repose sur la découverte selon laquelle l'apparition d'anomalies des centrosomes et la survenance d'un cancer sont en corrélation, et selon laquelle plus le degré d'anomalies des centrosomes est élevé, plus la probabilité d'apparition et la gravité du cancer sont importantes. L'invention concerne des méthodes de détection d'anomalies des centrosomes dans des échantillons tissulaires. L'invention propose des nouvelles méthodes prédictives et diagnostiques du cancer.
Doxsey Stephen J.
Pihan German
Smart & Biggar
University Of Massachusetts
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