G - Physics – 01 – N
Patent
G - Physics
01
N
G01N 33/574 (2006.01) G01N 27/62 (2006.01)
Patent
CA 2696458
The object of the present invention is to identify a molecule that is specifically recognized by antibody RM2 in tissue or serum of a cancer patient, and provide a method for diagnosing cancer in a simple manner with high specificity using the molecule as an indicator. The present method comprises evaluating a risk or grade of malignancy of genitourinary cancer in a subject using the level of the haptoglobin .beta. chain to which antibody RM2 specifically binds or a fragment thereof in tissue or body fluid isolated from the subject as an indicator.
L'invention vise à proposer un procédé de diagnostic de cancer commode et extrêmement spécifique, qui comprend la spécification d'une molécule reconnue de façon spécifique par l'anticorps RM2 dans un tissu ou le sérum d'un patient atteint d'un cancer, puis le ciblage de la molécule. A savoir, la possibilité de maladie ou la malignité d'un cancer génito-urinaire d'un patient est évaluée par l'utilisation, en tant qu'indication, du taux de chaîne ß de l'haptoglobine, auquel se lie spécifiquement l'anticorps RM2, ou de son fragment, dans un tissu ou fluide corporel prélevé à partir du patient.
Arai Yoichi
Saito Seiichi
Smart & Biggar
Tohoku Technoarch Co. Ltd.
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