Cancer gene therapeutic drug

Details Cancer gene therapeutic drug Cancer gene therapeutic drug

A - Human Necessities

61

K

A61K 48/00 (2006.01) A61K 31/409 (2006.01) A61K 33/26 (2006.01) A61K 35/12 (2006.01) A61K 35/76 (2006.01) A61P 35/00 (2006.01) C12N 15/00 (2006.01)

Patent

CA 2542337

An oncogene therapeutic drug which contains a carrier cell having been infected with an oncolytic virus so as to treat a tumor cell with the virus within the living body. As the carrier cell, any of an A549 cell, a 293 cell, an SW626 cell and an HT-3 cell showing a potent antitumor effect is used. Because of using such a cell having a high antitumor effect both in vitro and in vivo as the carrier cell, an enhanced antitumor effect can be established compared with conventional carrier cells.

L'invention concerne un médicament de traitement anticancéreux contenant une cellule vectrice qui a été infectée par un virus oncolytique de manière à pouvoir traiter une cellule tumorale, au moyen du virus, dans un corps vivant. Une cellule de type A549, 293, SW626 ou HT-3 présentant un effet antitumoral puissant peut être utilisée en tant que cellule vectrice. L'utilisation d'une cellule présentant un effet antitumoral puissant, à la fois in vitro et in vivo, en tant que cellule vectrice permet d'obtenir un effet antitumoral accru par rapport celui de cellules vectrices traditionnelles.

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