A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 35/00 (2006.01) C12N 15/85 (2006.01)
Patent
CA 2648067
Cellular compositions and methods for inducing an immune response to tumor cells are described. The cellular compositions include a tumor antigen and cells that have been modified to express a cytokine and one or more of a tumor antigen, an anti-CTLA4 antibody and an additional cytokine. The cellular compositions find utility in methods for treating cancer.
L'invention concerne des compositions cellulaires et des méthodes pour induire une réponse immunitaire à des cellules tumorales. Les compositions cellulaires comprennent un antigène tumoral et des cellules qui ont été modifiées pour exprimer une cytokine et un ou plusieurs éléments parmi un antigène tumoral, un anticorps anti-CTLA4 et une cytokine supplémentaire. Les compositions cellulaires sont utiles dans des méthodes de traitement de cancer.
Allison James
Jooss Karin
Simmons Andrew
Biosante Pharmaceuticals Inc.
Cell Genesys Inc.
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
The Regents Of The University Of California
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