Cancer-linked genes as targets for chemotherapy

Details Cancer-linked genes as targets for chemotherapy Cancer-linked genes as targets for chemotherapy

C - Chemistry, Metallurgy

12

Q

C12Q 1/68 (2006.01) A61K 39/00 (2006.01) C07K 14/47 (2006.01) G01N 33/50 (2006.01) G01N 33/574 (2006.01)

Patent

CA 2425643

Cancer-linked gene sequences, and derived amino acid sequences, are disclosed along with processes for assaying potential antitumor agents based on their modulation of the expression of these cancer-linked genes. Also disclosed are antibodies that react with the disclosed polypeptides and methods of diagnosing and treating cancer using the gene sequences. A novel gene and polypeptide are also disclosed.

L'invention concerne des séquences de gènes liés au cancer, des séquences d'acides aminés dérivées et des méthodes destinées à analyser des agents antitumoraux potentiels sur la base de leur modulation de l'expression de ces gènes liés au cancer. La présente invention se rapporte également à des anticorps réagissant avec les polypeptides de l'invention, ainsi qu'à des méthodes destinées au diagnostic et au traitement du cancer au moyen de ces séquences de gènes. Ladite invention concerne enfin un nouveau gène et un nouveau polypeptide.

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