Cancer monitoring and therapeutics

Details Cancer monitoring and therapeutics Cancer monitoring and therapeutics

C - Chemistry, Metallurgy

12

N

C12N 15/54 (2006.01) A61K 31/496 (2006.01) A61K 31/7088 (2006.01) A61K 31/728 (2006.01) A61K 38/16 (2006.01) A61K 39/395 (2006.01) A61K 45/00 (2006.01) A61K 48/00 (2006.01) C12Q 1/02 (2006.01) C12Q 1/68 (2006.01) G01N 33/53 (2006.01)

Patent

CA 2441681

Provided for are three novel isoenzyme variants of the human Hyaluronan Synthase gene, HAS 1 V a, HAS 1 Vb, and HAS 1 Vc. Also provided is a method for assessing disease, or susceptibility to disease, in a patient; in which a cell or sample of a cell population is mixed with at least one compound which specifically binds to HAS 1 Va, HAS 1 Vb, HAS 1 Vc or HAS2 isoenzyme or isoenzyme variant genomic mRNA transcript or products arising therefrom; and methods of treatment.

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