Cancer related haptoglobin

Details Cancer related haptoglobin Cancer related haptoglobin

C - Chemistry, Metallurgy

12

P

C12P 21/00 (2006.01) A61K 31/336 (2006.01) A61K 39/385 (2006.01) A61K 39/39 (2006.01) A61K 39/395 (2006.01) C07K 14/435 (2006.01) C07K 14/47 (2006.01) C07K 16/18 (2006.01) C07K 16/30 (2006.01) C12N 9/10 (2006.01) G01N 33/574 (2006.01)

Patent

CA 2045552

Substantially pure preparations of Hpr protein are provided as well as methods of making these preparations from at least four different human cell sources: breast carcinoma cells, decidua cells; placental tissue and pregnancy serum. The Hpr protein has use as a diagnostic marker which correlates with early relapse and metastasis of breast and other cancers. The marker can be detected using immunological methods employing antibodies specific for Hpr protein and not cross-reactive with haptoglobins 1 or 2.

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