Cancer susceptibility variants on chr8q24.21

C - Chemistry – Metallurgy – 12 – Q

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C12Q 1/68 (2006.01)

Patent

CA 2667737

A region on chromosome 8q24.21 has been demonstrated to play a major role in particular forms of cancer. It has been discovered that certain markers and haplotypes are indicative of a susceptibility to particular cancers, including prostate cancer. Diagnostic applications for identifying a susceptibilty to cancer using these markers and haplotypes are described.

La présente invention concerne une région sur le chromosome 8q24.21 dont on a été démontré qu'elle joue un rôle important dans des formes particulières de cancer. On a découvert que certains marqueurs et haplotypes sont indicatifs d'une prédisposition à des cancers particuliers, y compris le cancer de la prostate. L'invention concerne des applications de diagnostic permettant d'identifier une prédisposition à un cancer à l'aide de ces marqueurs et haplotypes.

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