Cancer therapy

A - Human Necessities – 61 – K

Patent

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Details

A61K 39/00 (2006.01) A61K 45/06 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2476366

The present invention provides methods for treating a cancer patient. The methods rely on theobservation that cells of the immune system which target a tumour cell ("effector cells") clonallyexpand before a population of "regulator" or "suppressor" cells which down-regulate the activity of the immune cells which target the tumour cell. Methods are provided herein which stimulate effector cell production and also provides means for inhibiting the production of, limiting thefunction of, and/or destroying, regulator cells, in the treatment of cancer.

L'invention concerne des procédés destinés à traiter un patient atteint d'un cancer. Ces procédés s'appuient sur l'observation des cellules du système immunitaire qui ciblent une cellule tumorale ("cellules effectrices") s'étendant par clonage avant une population de cellules "régulatrices" ou "suppressives", lesquelles régulent vers le bas l'activité des cellules immunitaires ciblant la cellule tumorale. L'invention concerne également des procédés favorisant la production de cellules effectrices et produit des moyens permettant d'inhiber la production, limiter la fonction, et/ou détruire des cellules régulatrices, dans le traitement du cancer.

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