A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 39/395 (2006.01) A61K 31/337 (2006.01) A61K 51/10 (2006.01)
Patent
CA 2472893
The invention relates to a therapeutic system comprising (i) a radiolabelled antibody, which binds selectively to polymorphic epithelial mucin (PEM) such as the monoclonal antibody HMFG-1, and (ii) a chemotherapeutic agent, such as Taxotere ®. The radiolabelled antibody and chemotherapeutic agent are administered in combination with one another to produce a synergistic therapeutic effect.
L'invention se rapporte à un système thérapeutique comprenant (i) un anticorps radiomarqué, qui se fixe de manière sélective à une mucine épithéliale polymorphe (PEM) telle que l'anticorps monoclonal HMFG-1, et (ii) un agent chimiothérapeutique, tel qu'un Taxotere®. Ledit anticorps radiomarqué et l'agent chimiothérapeutique sont administrés en combinaison l'un avec l'autre, afin de produire un effet thérapeutique synergique.
Antisoma Plc
Borden Ladner Gervais Llp
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