A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/7068 (2006.01) A61K 31/517 (2006.01) A61P 35/00 (2006.01)
Patent
CA 2569139
The present invention relates to a method of treating cancer in a mammal by administration of 4-quinazolinamines and at least one additional anti- neoplastic compound. In particular, the method relates to a methods of treating cancers by administration of N-{3-chloro-4-[(3-fluorobenzyl) oxy]phenyl}-6-[5-({[2-(methanesulphonyl) ethyl]amino} methyl)-2-furyl]-4- quinazolinamine and salts and solvates thereof in combination with at least one additional anti-neoplastic compound.
La présente invention concerne une méthode de traitement d'un cancer chez un mammifère, par administration de 4-quinazolinamines et d'au moins un composé anti-néoplastique complémentaire. On décrit, en particulier, des méthodes de traitement de cancers, par administration de N-{3-chloro-4-[(3-fluorobenzyl) oxy]phényl}-6-[5-({[2-(méthanesulphonyl) éthyl]amino} méthyl)-2-furyl]-4-quinazolinamine et de ses sels et solvates, en association avec au moins un composé anti-néoplastique complémentaire.
Berger Mark S.
Gilmer Tona Morgan
Pandite Arundathy Nirmalini
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
Smithkline Beecham (cork) Limited
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