Cancer treatment using proanp peptides

Details Cancer treatment using proanp peptides Cancer treatment using proanp peptides

A - Human Necessities

61

K

A61K 38/22 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2518550

The present invention includes a method of utilizing four peptide hormones to inhibit the growth of cancer(s). A dramatic decrease in the number of human pancreatic adenocarcinoma cells (Le., the type of cancer with the highest mortality, with patients only surviving four months) was observed responsive to treatment. The application of the invention would be to utilize one or more of these peptide hormones alone and/or in combination to treat cancer. The ability of these peptide hormones to decrease the number of adenocarcinoma cells has implications for adenocarcinomas at other sites in the body with the majority of cancers of the breast, colon and prostate also being adenocarcinomas. Adenocarcinomas also occur in the lung and other tissues. Treatment of a wide variety of cancers in addition to adenocarcinomas is anticipated by the present invention.

L'invention concerne une méthode de traitement mettant en application quatre hormones peptidiques afin d'inhiber la croissance de différents types de cancer. On a observé à la suite du traitement une diminution considérable du nombre de cellules de l'adénocarcinome pancréatique humain (type de cancer présentant la mortalité la plus élevée et une survie non supérieure à quatre mois). Le but de l'invention consisterait à utiliser une ou plusieurs de ces hormones peptidiques seules ou combinées en thérapie du cancer. Leur capacité à diminuer le nombre de cellules cancéreuses s'étend à des adénocarcinomes d'autres parties du corps, la majorité des cancers du sein, du côlon et de la prostate étant également des adénocarcinomes. Ceux-ci peuvent également apparaître dans le poumon ou dans d'autres tissus. L'invention permet d'anticiper le traitement d'un grand nombre de types de cancer en plus des adénocarcinomes.

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