Cancer treatment using viruses, fluoropyrimidines and...

Details Cancer treatment using viruses, fluoropyrimidines and... Cancer treatment using viruses, fluoropyrimidines and...

A - Human Necessities

61

K

A61K 48/00 (2006.01) C07K 5/00 (2006.01)

Patent

CA 2612949

Mammalian subjects having a neoplasm are treated with a virus, a fluoropyrimidine, for example 5-fluorouracil, and a camptothecin compound. The virus is selected from the group consisting of a Newcastle disease virus, a measles virus, a vesicular stomatitis virus, an influenza virus, a Sindbis virus, a picornavirus, and a myxoma virus.

Des sujets mammifères présentant un néoplasme sont traités par un virus, un fluoropyrimidine, par exemple 5-fluorouracile, ainsi que par un composé de camptothécine. Le virus est sélectionné dans le groupe constitué par un virus de la maladie de Newcastle, un virus de la rougeole, un virus de la stomatite vésiculeuse, un virus grippal A, un virus Sindbis, un picornavirus, et un virus myxome.

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