Cancer treatment with epothilones

Details Cancer treatment with epothilones Cancer treatment with epothilones

A - Human Necessities

61

K

A61K 31/426 (2006.01) A61K 31/427 (2006.01) A61K 45/06 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2537057

The present invention relates to an in vivo regimen for the treatment of a proliferative disease, preferably a tumor that is refractory to treatment with one or more chemotherapeutics other than a epothilone, where an epothilone is administered in a loading dose followed by at least 1 maintenance dose.

L'invention concerne un schéma posologique in vivo permettant de traiter une maladie proliférative, de préférence une tumeur réfractaire à un traitement faisant appel à un ou plusieurs agent(s) chimiothérapeutique(s) autre(s) qu'une épothilone. Selon l'invention, une épothilone est administrée en une dose d'attaque suivie d'au moins une dose d'entretien.

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