Cancer treatment with topoisomerase-ii inhibitor, a...

A - Human Necessities – 61 – K

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A61K 31/7048 (2006.01) A61K 31/496 (2006.01) A61K 41/00 (2006.01) A61N 5/10 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2557857

The present invention relates to a method of treatment of a tumour cell which comprises administering to a subject in need of treatment an effective amount of a topoisomerase-II poison, e.g. etoposide, in combination with a bis- dioxypiperazine, e.g. dexrazoxane wherein said subject is further treated with radiation.

La présente invention concerne une méthode permettant de traiter une cellule tumorale, laquelle méthode consiste à administrer à un sujet nécessitant un traitement, une quantité efficace d'un poison de la topoisomérase-II, par exemple, l'étoposide, conjointement avec un bis-dioxypiperazine, par exemple le dexrazoxane. Dans cette méthode le sujet est également traité par radiothérapie.

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