Cancer treatments

Details Cancer treatments Cancer treatments

A - Human Necessities

61

K

A61K 31/415 (2006.01)

Patent

CA 2585659

Methods and compositions for treating cancers characterized by death-resistant cancer cells are described. In general, such methods involve administration of a therapeutically effective amount of a compound that induces mitotic catastrophe in the some, and preferably most or all, of the cancerous cells. Methods for assessing the efficacy of such treatments are also provided.

Cette invention concerne des méthodes et des compositions de traitement de cancers caractérisés par la présence de cellules cancéreuses résistant à l'apoptose. De façon générale, ces méthodes passent par l'administration d'une dose thérapeutiquement efficace d'un composé qui induit une catastrophe mitotique pour certaines, et de préférence pour la majorité ou la totalité des cellules cancéreuses. Sont également décrites des méthodes d'évaluation de l'efficacité de tels traitements.

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